Veritas In Silico Inc.
130A・Growth Market・Pharmaceuticals
Business
Veritas In Silico, Inc. is a drug discovery biotech company that leverages its proprietary AI drug discovery platform "aibVIS" to pursue the creation of mRNA-targeted small-molecule drugs, an approach that has been difficult to achieve with conventional drug discovery technologies. Founded in 2016, the company listed on the TSE Growth Market in 2024. As part of its platform business, it conducts joint drug discovery research with four domestic pharmaceutical companies—Toray, Shionogi, RaQualia Pharma, and Takeda Pharmaceutical—while also advancing in-house drug discovery of nucleic acid drugs (ASOs) as part of its pipeline business. The company targets a wide range of disease areas, including cancer, central nervous system disorders, and rare diseases, aiming to address unmet medical needs. Since 2025, the company has been transitioning to a hybrid business model that combines the platform-type and pipeline-type approaches.
Business Model
In the platform business, the company enters into joint drug discovery research agreements with pharmaceutical companies, progressively earning upfront contract payments, research support funding, research milestones, development milestones, royalties, and sales milestones. In the pipeline business, the company independently creates drug candidate compounds such as ASOs, and generates large upfront payments and post-development revenue through out-licensing agreements with pharmaceutical companies. The company has also devised creative funding arrangements, such as its joint research with Mitsubishi Gas Chemical Company, in which it secures joint research funding (expected to receive half of the total ¥300 million, i.e., ¥150 million) in exchange for manufacturing rights.
Company Strengths
Regarding the core technology underlying the ibVIS platform (a business model for small-molecule drug discovery targeting RNA), the company has secured patent rights across three major jurisdictions: Japan (obtained 2020), Europe (January 2025), and the United States (July 2025). It has further strengthened multilayered technological exclusivity through intellectual property by adding the Perfusio DDS patent (Japan, obtained December 2025) and an ASO substance patent (application filed).
The ibVIS platform's target exploration success rate is approximately 98%, and its screening success rate is approximately 96%, resulting in an overall success rate of approximately 94% from mRNA selection through hit compound acquisition (as of end of December 2025). More than 100 drug discovery target genes have been disclosed by pharmaceutical companies, demonstrating a track record of applicability across a broad range of disease areas including cancer, central nervous system disorders, and rare diseases.
The company has entered into joint drug discovery research agreements with Toray Industries (July 2021), Shionogi & Co. (November 2021), Raqualia Pharma (December 2022), and Takeda Pharmaceutical Company (June 2023). Based on existing contracts disclosed in the securities report, the short-term revenue potential from research support funds and milestone payments receivable is up to ¥1,940 million, of which ¥920 million has already been received.
ENVALITH's Perspective
Performance Trend
Business revenue decelerated sharply from ¥360 million in FY2023 to ¥195 million in FY2024 to ¥91 million in FY2025, and cumulative Q1 FY2026 revenue was ¥18 million (down 26% year on year). The operating loss widened to ¥122 million on a cumulative Q1 basis (versus ¥81 million in the same period of the prior year). Research and development expenses increased to ¥67 million in Q1 (versus ¥42 million in the same period of the prior year), while the structural issue of stagnant revenue growth persisted. In addition, an impairment loss on tangible fixed assets of ¥135 million was recorded as an extraordinary loss, causing the quarterly net loss to balloon to ¥256 million. There is no change to the full-year earnings forecast (business revenue of ¥113 million, operating loss of ¥569 million), and the company states that there has been no particular impact from the external environment (such as the situation in the Middle East and surging energy prices).
Growth Strategy
Advancing four pillars: aibVIS platform enhancement, acquisition of new contracts, animal testing for in-house pipeline, and commercialization of Perfusio
Upgrade from ibVIS® to aibVIS completed in January 2026. Continuing outreach to domestic and international pharmaceutical companies interested in mRNA-targeted small molecule and nucleic acid drugs. Negotiations toward formal contract execution with SpiroChem AG (Switzerland) are in progress.
Joint drug discovery research with Toray, Shionogi & Co., RaQualia Pharma, and Takeda Pharmaceutical progressed as planned in Q1 FY2026 (ending March 2026). The company aims to secure stable research support income and build up revenue through milestone achievements.
The disease treatment project using ASO targeting ischemic acute kidney failure following cardiovascular surgery is progressing smoothly, with preparations underway for animal testing as of Q1 FY2026 (ending March 2026). Joint research on nucleic acid drugs with Mitsubishi Gas Chemical is also advancing in parallel.
For Perfusio, a drug delivery system using a catheter conceived by the company, concretization of the execution plan advanced in Q1 FY2026 (ending March 2026). Reduction in development period and cost is expected, but the timing and scale of commercialization remain undetermined.
Last updated: July 17, 2026

